Three-time Oscar nominee Christopher Nolan (Interstellar, Inception) directs this critically acclaimed mystery. Leonard (Guy Pearce) is tracking down the man who raped and murdered his wife. The difficulty, however, of locating his wife's killer is compounded by the fact that he suffers from a rare, untreatable form of memory loss. Although he can recall details of life before his accident, Leonard cannot remember what happened fifteen minutes ago, where he's going, or why.

This star-studded drama follows the story of Adam Stein (Jeff Goldblum, Jurassic Park, The Grand Budapest Hotel), a charismatic patient at a mental institution for Holocaust survivors in Israel, in 1961. He reads minds and confounds his doctors, lead by Dr. Nathan Gross (Derek Jacobi, The King's Speech, Gladiator). Before the war, in Berlin, Adam was an entertainer--cabaret impresario, circus owner, magician, musician--loved by audiences and Nazis alike until he finds himself in a concentration camp, confronted by Commandant Klein (Willem Dafoe, Plantoon, Spiderman). Adam survives the camp by becoming the Commandant's "dog," entertaining him while his wife and daughter are sent off to die. Years later we find him at the Institute. One day, Adam smells something, hears a sound. "Who brought a dog in here?" he asks Gross. Gross denies there is a dog but Adam finds him--a young boy raised in a basement on a chain. Adam and the boy see and recognize each other as dogs--and their journey begins.