Publisher's Weekly Review

Dermatologist and bestselling author Perricone (The Perricone Prescription, etc.) takes his extensive knowledge of skin care and aging to a deeper level in his latest volume, explaining the science behind his theory that aging is intimately tied to inflammation. Perricone claims that certain peptides and neuropeptides (proteinlike substances found within the body) are key to maintaining health and longevity, and our food choices can boost their positive power. How one ages, Perricone says, largely depends on what one eats; the wrong choices have a crucial impact on wrinkles, degenerative diseases such as cancer and Alzheimer's, and can accelerate aging. Although Perricone doesn't offer a magic potion, he does claim his 28-day plan will decelerate the aging process by fighting inflammation. While the author's rather pricey topical products ($95 for a "face firming activator") are part of this complex program, the bulk of the text focuses on affordable options, such as purchasing "rainbow foods" (fresh fruits and vegetables), liberally using such healthy spices as oregano and basil, and consuming "superfoods" like barley, beans and hot peppers. Perricone also recommends natural supplements, including coenzyme Q10 and vitamin C ester, and provides a detailed plan that combines diet, exercise, supplements and topicals. Though the science-based text is sometimes weighty, readers seeking the logic behind their skin and health-care decisions won't be disappointed by the promises Perricone makes. Agent, Anne Sellaro. (Oct. 27) Forecast: Perricone is well-known and media savvy, and his products are sold in upscale stores. A hefty ad campaign (including print, TV, billboard and transit ads) should result in robust sales. (c) Copyright PWxyz, LLC. All rights reserved