Age later : health span, life span, and the new science of longevity / Nir Barzilai, M.D. with Toni Robino.

Title :

Age later : health span, life span, and the new science of longevity

Author:

Barzilai, Nir,

Format:

Books

Summary:

Is it possible to grow older without getting sicker? Can you look and feel fifty through your eighties and nineties? Barzilai's life's work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including 'the big four': diabetes, cancer, heart disease, and Alzheimer's. His studies include SuperAgers: individuals who maintain active lives well into their nineties and even beyond-- and reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline. Here Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process.

Language:

English

ISBN - ISSN:

9781432884796

1432884794

Physical Description:

373 pages (large print) : illustrations ; 22 cm.

Contents:

Introduction -- One hundred years young -- Why we age -- Cholesterol: is more better? -- Growth hormone: less is more -- Unraveling the longevity mystery deep inside our cells -- The quest to prove aging can be targeted -- Making eighty the new sixty -- Stop the clock -- Bright horizons.

Subject:

Longevity.

Health.

Aging -- Psychological aspects.

Large type books.

Series:

Thorndike Press large print nonfiction series.

First Title value, for Searching:

Age later : health span, life span, and the new science of longevity / Nir Barzilai, M.D. with Toni Robino.

Holds: Copies:

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Library	Audience	Home Location	Material Type	Shelf Number	Status
Searching... Henington-Alief	Adult	Large print	Large print book	612.68 B296	Searching... Unknown
Searching... Kendall	Adult	Large print	Large print book	612.68 B296	Searching... Unknown
Searching... Looscan	Adult	Large print	Large print book	612.68 B296	Searching... Unknown

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Summary

Founder of the Institute for Aging Research at the Albert Einstein College of Medicine, Dr. Nir Barzilai is one of the leading pioneers of longevity research. His life's work is tackling the challenges of delaying or preventing aging. In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers - individuals who maintain active lives well into their nineties and even beyond - and the scientific discoveries that show we can mimic some of their natural Resistance to the aging process. Book jacket.

Introduction	p. 13
1 One Hundred Years Young	p. 23
The Mysteries of Aging	p. 28
What Makes SuperAgers Stay Healthy?	p. 33
Studying Centenarians	p. 37
Designing a Study Without a Control Group	p. 48
Meeting Our First AJ Centenarians and Their Offspring	p. 52
A Perfect Genome?	p. 56
Centenarians' Interactions with Their Environments	p. 58
Do as I Say, Not as I Do	p. 70
2 Why We Age	p. 74
Recent Theories	p. 83
The Search for Protection from Aging	p. 90
Eating Less May Lead to More Healthy Years	p. 97
Unlocking the Secrets in Fat	p. 99
Caloric Restriction: A Mixed Bag of Effects	p. 109
Aging Begins Before We're Born	p. 114
SuperAgers' Top Secrets	p. 115
3 Cholesterol: Is More Better?	p. 119
Unlocking Cholesterol's Longevity Secrets	p. 124
Are There Really Good Gene Mutations?	p. 129
Solving the Mystery of Helpful Gene Mutations	p. 132
The Benefits of CETP Personified	p. 140
A Mutation That Adds Years to Life Span?	p. 146
4 Growth Hormone: Less Is More	p. 149
Less Growth May Lead to an Exceptionally Long Life	p. 151
Growth Hormone Clues from Our Centenarians	p. 154
Epigenetic Mechanisms Can Increase Longevity	p. 163
Making the Most of Our Findings	p. 169
Growth Hormones Don't "Grow" Life Span	p. 173
5 Unraveling the Longevity Mystery Deep Inside Our Cells	p. 177
A Match Made on Earth	p. 178
Mitochondria's Hidden Purpose	p. 180
Resilient to the End	p. 187
A CohBar Is Born	p. 198
Searching for Promising Peptides	p. 204
6 The Quest to Prove Aging Can Be Targeted	p. 209
Choosing an Existing Drug to Prove Our Point	p. 220
Getting the FDA on Board	p. 225
How the TAME Study Works	p. 228
Who's Going to Pay for All of This?	p. 235
Metformin Is the Tool, Not the Goal	p. 241
7 Making Eighty the New Sixty	p. 245
The Price of Progress	p. 253
Collaboration Is the Key to Speed	p. 254
Long, Healthy Life Span Versus Immortality	p. 258
The Gap Between Making Drugs and Making Drugs Available	p. 265
8 Stop the Clock	p. 268
How Old Is Old?	p. 271
Use It or Lose It	p. 275
Antioxidants and Hormesis	p. 279
Thriving in the Shadow of Stress	p. 282
Preventing the Loss of Muscle Mass as We Age	p. 288
Exercise Plus Metformin	p. 289
Feeding Our Longevity	p. 291
Hydrating Wisely	p. 297
Prevent Obesity	p. 299
Nutraceuticals Are in the Works	p. 305
The Magic Pills We've Been Wishing For	p. 310
When We Eat Matters	p. 313
Our DNA Has Something to Say	p. 321
Stay Mentally Sharp	p. 326
Other Promising Practices	p. 336
How to Decide What's Good for You	p. 341
9 Bright Horizons	p. 343
The Unparalleled Power of Omics	p. 344
Personalized Medicine	p. 350
Advances in Early Detection	p. 352
Pioneering Explorations	p. 354
Reversing Cellular Age	p. 358
Genetic Engineering	p. 360
Acknowledgments	p. 363

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Summary

Summary

Table of Contents